【進度】
1. Introduction to natural bio-products
2. How to approach the isolation of a natural product
3. Initial extraction and product capture
4. Supercritical fluid methods
5. Isolation by low-pressure column chromatography
6. Isolation by ion-exchange methods
7. Isolation by planar chromatography
8. Isolation by preparative HPLC
9. Crystallization and final stages of purification
10. Separation by high-speed countercurrent chromatography
11. Partial identification of natural products
12. Purification of water-soluble natural products
13. Special problems with the extraction of plants
14. Scale-up of natural products isolation
15. Follow-up of natural products isolation
16. Overall discussion

【參考書目】
1.Natural Products Isolation / by Richard J.P. Cannell : Humana Press Inc., Totowa New Jersey, 1998.
2.Encyclopedia of Separation Science/ by Ian D. Wilsion et al., San Diego, Calif.; London: Academic Press, 2000.
3.Separation and Purification Techniques in Biotechnology/ by Frederick J. Dechow, Park Ridge, NJ: Noyes Publications, 1989.
4.Chromatography and Capillary electrophoresis in food analysis/ by Hilmer Sorensen et al., Cambridge: Royal Society of Chemistry, 1999.
【成績評量方式】
出缺席狀況(10%)、期中考試(60%)、期末報告(30%)